BDBM50021701 CHEMBL3297954

SMILES: Cl.C1COc2cc3c(Nc4cccc(c4)-c4ccco4)ncnc3cc2O1

InChI Key: InChIKey=GAJQPJGSOQBXHY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50021701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50021701 (CHEMBL3297954) Show SMILES Cl.C1COc2cc3c(Nc4cccc(c4)-c4ccco4)ncnc3cc2O1 Show InChI InChI=1S/C20H15N3O3.ClH/c1-3-13(17-5-2-6-24-17)9-14(4-1)23-20-15-10-18-19(26-8-7-25-18)11-16(15)21-12-22-20;/h1-6,9-12H,7-8H2,(H,21,22,23);1H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...				J Med Chem 57: 4598-605 (2014) Article DOI: 10.1021/jm500034j BindingDB Entry DOI: 10.7270/Q2KH0PW0
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50021701 (CHEMBL3297954) Show SMILES Cl.C1COc2cc3c(Nc4cccc(c4)-c4ccco4)ncnc3cc2O1 Show InChI InChI=1S/C20H15N3O3.ClH/c1-3-13(17-5-2-6-24-17)9-14(4-1)23-20-15-10-18-19(26-8-7-25-18)11-16(15)21-12-22-20;/h1-6,9-12H,7-8H2,(H,21,22,23);1H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of Src (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysis				J Med Chem 57: 4598-605 (2014) Article DOI: 10.1021/jm500034j BindingDB Entry DOI: 10.7270/Q2KH0PW0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50021701 (CHEMBL3297954) Show SMILES Cl.C1COc2cc3c(Nc4cccc(c4)-c4ccco4)ncnc3cc2O1 Show InChI InChI=1S/C20H15N3O3.ClH/c1-3-13(17-5-2-6-24-17)9-14(4-1)23-20-15-10-18-19(26-8-7-25-18)11-16(15)21-12-22-20;/h1-6,9-12H,7-8H2,(H,21,22,23);1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of Abl1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...				J Med Chem 57: 4598-605 (2014) Article DOI: 10.1021/jm500034j BindingDB Entry DOI: 10.7270/Q2KH0PW0
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50021701 (CHEMBL3297954) Show SMILES Cl.C1COc2cc3c(Nc4cccc(c4)-c4ccco4)ncnc3cc2O1 Show InChI InChI=1S/C20H15N3O3.ClH/c1-3-13(17-5-2-6-24-17)9-14(4-1)23-20-15-10-18-19(26-8-7-25-18)11-16(15)21-12-22-20;/h1-6,9-12H,7-8H2,(H,21,22,23);1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analys...				J Med Chem 57: 4598-605 (2014) Article DOI: 10.1021/jm500034j BindingDB Entry DOI: 10.7270/Q2KH0PW0
					More data for this Ligand-Target Pair