BDBM50021720 CHEMBL3298983

SMILES: C[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc2cc[nH]c2c1

InChI Key: InChIKey=WQZCQSZZPWAGRX-OAHLLOKOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50021720 (CHEMBL3298983) Show SMILES C[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc2cc[nH]c2c1 |r| Show InChI InChI=1S/C23H28N6O2/c1-15(17-3-2-16-4-8-24-20(16)12-17)26-23(30)29-9-5-18-13-25-22(28-21(18)14-29)27-19-6-10-31-11-7-19/h2-4,8,12-13,15,19,24H,5-7,9-11,14H2,1H3,(H,26,30)(H,25,27,28)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc Curated by ChEMBL					Assay Description Inhibition of Cdk2 (unknown origin)				Bioorg Med Chem Lett 24: 2635-9 (2014) Article DOI: 10.1016/j.bmcl.2014.04.068 BindingDB Entry DOI: 10.7270/Q2FQ9Z54
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50021720 (CHEMBL3298983) Show SMILES C[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc2cc[nH]c2c1 |r| Show InChI InChI=1S/C23H28N6O2/c1-15(17-3-2-16-4-8-24-20(16)12-17)26-23(30)29-9-5-18-13-25-22(28-21(18)14-29)27-19-6-10-31-11-7-19/h2-4,8,12-13,15,19,24H,5-7,9-11,14H2,1H3,(H,26,30)(H,25,27,28)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc Curated by ChEMBL					Assay Description Inhibition of ERK2 in human HepG2 cells assessed as P90RSK phosphorylation at Ser380 after 1.5 hrs by fluorescence assay				Bioorg Med Chem Lett 24: 2635-9 (2014) Article DOI: 10.1016/j.bmcl.2014.04.068 BindingDB Entry DOI: 10.7270/Q2FQ9Z54
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50021720 (CHEMBL3298983) Show SMILES C[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc2cc[nH]c2c1 |r| Show InChI InChI=1S/C23H28N6O2/c1-15(17-3-2-16-4-8-24-20(16)12-17)26-23(30)29-9-5-18-13-25-22(28-21(18)14-29)27-19-6-10-31-11-7-19/h2-4,8,12-13,15,19,24H,5-7,9-11,14H2,1H3,(H,26,30)(H,25,27,28)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal 6-His-tagged ERK2 expressed in Escherichia coli using S/T17 as substrate after 30 mins by spectrophotometr...				Bioorg Med Chem Lett 24: 2635-9 (2014) Article DOI: 10.1016/j.bmcl.2014.04.068 BindingDB Entry DOI: 10.7270/Q2FQ9Z54
					More data for this Ligand-Target Pair