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BDBM50021817 CHEMBL3298826

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2sc3nc(OC)c(Cl)c(C)c3c2N)CC1

InChI Key: InChIKey=RULOOZJTFYDVKV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021817   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50021817
PNG
(CHEMBL3298826)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2sc3nc(OC)c(Cl)c(C)c3c2N)CC1
Show InChI InChI=1S/C25H32ClN5O3S/c1-16-19-21(27)22(35-25(19)29-24(34-3)20(16)26)23(32)28-10-6-7-11-30-12-14-31(15-13-30)17-8-4-5-9-18(17)33-2/h4-5,8-9H,6-7,10-15,27H2,1-3H3,(H,28,32)
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Similars
Article
PubMed
 6.30n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human D2L receptor expressed in FlpIn CHO cell membrane after 3 hrs by liquid scintillation counting analysis

J Med Chem 57: 4924-39 (2014)


Article DOI: 10.1021/jm500457x
BindingDB Entry DOI: 10.7270/Q29Z96FS
More data for this
Ligand-Target Pair