BDBM50021847 5-[2-(4-Methyl-piperazin-1-yl)-acetyl]-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one::CHEMBL276771

SMILES: CN1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1

InChI Key: InChIKey=RYIVUUNQOYFPOH-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50021847 (5-[2-(4-Methyl-piperazin-1-yl)-acetyl]-5,10-dihydr...) Show SMILES CN1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1 Show InChI InChI=1S/C20H22N4O2/c1-22-10-12-23(13-11-22)14-19(25)24-17-8-4-2-6-15(17)20(26)21-16-7-3-5-9-18(16)24/h2-9H,10-14H2,1H3,(H,21,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...				J Med Chem 30: 1378-82 (1987) BindingDB Entry DOI: 10.7270/Q25B04QP
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50021847 (5-[2-(4-Methyl-piperazin-1-yl)-acetyl]-5,10-dihydr...) Show SMILES CN1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1 Show InChI InChI=1S/C20H22N4O2/c1-22-10-12-23(13-11-22)14-19(25)24-17-8-4-2-6-15(17)20(26)21-16-7-3-5-9-18(16)24/h2-9H,10-14H2,1H3,(H,21,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Binding affinity towards muscarinic receptor of gastric fundus containing Muscarinic acetylcholine receptor M2				J Med Chem 31: 1169-74 (1988) BindingDB Entry DOI: 10.7270/Q2DV1HW6
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50021847 (5-[2-(4-Methyl-piperazin-1-yl)-acetyl]-5,10-dihydr...) Show SMILES CN1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1 Show InChI InChI=1S/C20H22N4O2/c1-22-10-12-23(13-11-22)14-19(25)24-17-8-4-2-6-15(17)20(26)21-16-7-3-5-9-18(16)24/h2-9H,10-14H2,1H3,(H,21,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortex				J Med Chem 31: 1169-74 (1988) BindingDB Entry DOI: 10.7270/Q2DV1HW6
					More data for this Ligand-Target Pair