BDBM50021996 Ac-His-Pro-Phe-His-Statine-Leu-Val-NH2::CHEMBL295219

SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O

InChI Key: InChIKey=UZNVPIMEQLVCMY-BLYJGPFASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Rattus norvegicus)	BDBM50021996 (Ac-His-Pro-Phe-His-Statine-Leu-Val-NH2 | CHEMBL295...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C47H70N12O9/c1-26(2)16-33(39(61)21-40(62)54-34(17-27(3)4)45(66)58-41(28(5)6)42(48)63)55-44(65)36(19-31-22-49-24-51-31)56-43(64)35(18-30-12-9-8-10-13-30)57-46(67)38-14-11-15-59(38)47(68)37(53-29(7)60)20-32-23-50-25-52-32/h8-10,12-13,22-28,33-39,41,61H,11,14-21H2,1-7H3,(H2,48,63)(H,49,51)(H,50,52)(H,53,60)(H,54,62)(H,55,65)(H,56,64)(H,57,67)(H,58,66)/t33-,34-,35-,36-,37-,38+,39-,41-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibitory activity against rat plasma renin in vitro.				J Med Chem 31: 1679-86 (1988) BindingDB Entry DOI: 10.7270/Q2NC61TR
					More data for this Ligand-Target Pair