BDBM50022005 Ac-His-Pro-Phe-His-Statine-Leu-Phe-NH2::CHEMBL266410

SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=SBISAPJFLPILLA-ZUVHIXNHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50022005 (Ac-His-Pro-Phe-His-Statine-Leu-Phe-NH2 | CHEMBL266...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C51H70N12O9/c1-30(2)19-37(44(65)25-45(66)58-39(20-31(3)4)47(68)60-38(46(52)67)21-33-13-8-6-9-14-33)59-49(70)41(23-35-26-53-28-55-35)61-48(69)40(22-34-15-10-7-11-16-34)62-50(71)43-17-12-18-63(43)51(72)42(57-32(5)64)24-36-27-54-29-56-36/h6-11,13-16,26-31,37-44,65H,12,17-25H2,1-5H3,(H2,52,67)(H,53,55)(H,54,56)(H,57,64)(H,58,66)(H,59,70)(H,60,68)(H,61,69)(H,62,71)/t37-,38-,39-,40-,41-,42-,43+,44-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Compound was tested for its inhibitory activity against human plasma renin				J Med Chem 31: 1679-86 (1988) BindingDB Entry DOI: 10.7270/Q2NC61TR
					More data for this Ligand-Target Pair
Renin (Rattus norvegicus)	BDBM50022005 (Ac-His-Pro-Phe-His-Statine-Leu-Phe-NH2 | CHEMBL266...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C51H70N12O9/c1-30(2)19-37(44(65)25-45(66)58-39(20-31(3)4)47(68)60-38(46(52)67)21-33-13-8-6-9-14-33)59-49(70)41(23-35-26-53-28-55-35)61-48(69)40(22-34-15-10-7-11-16-34)62-50(71)43-17-12-18-63(43)51(72)42(57-32(5)64)24-36-27-54-29-56-36/h6-11,13-16,26-31,37-44,65H,12,17-25H2,1-5H3,(H2,52,67)(H,53,55)(H,54,56)(H,57,64)(H,58,66)(H,59,70)(H,60,68)(H,61,69)(H,62,71)/t37-,38-,39-,40-,41-,42-,43+,44-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibitory activity against rat plasma renin in vitro.				J Med Chem 31: 1679-86 (1988) BindingDB Entry DOI: 10.7270/Q2NC61TR
					More data for this Ligand-Target Pair