BDBM50022154 6-Benzylamino-1H-pyrimidine-2,4-dione::CHEMBL86482

SMILES: O=c1cc(NCc2ccccc2)[nH]c(=O)[nH]1

InChI Key: InChIKey=NORSBFZJRBPBQZ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase III (Bacillus subtilis)	BDBM50022154 (6-Benzylamino-1H-pyrimidine-2,4-dione | CHEMBL8648...) Show SMILES O=c1cc(NCc2ccccc2)[nH]c(=O)[nH]1 Show InChI InChI=1S/C11H11N3O2/c15-10-6-9(13-11(16)14-10)12-7-8-4-2-1-3-5-8/h1-6H,7H2,(H3,12,13,14,15,16)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration producing 50% inhibition of Bacillus subtilis DNA topoisomerase III in the presence of dGTP using DNA Polymerase assay				J Med Chem 29: 676-81 (1986) BindingDB Entry DOI: 10.7270/Q2MP528D
					More data for this Ligand-Target Pair
Thymidine Phosphorylase (TP) (Homo sapiens (Human))	BDBM50022154 (6-Benzylamino-1H-pyrimidine-2,4-dione | CHEMBL8648...) Show SMILES O=c1cc(NCc2ccccc2)[nH]c(=O)[nH]1 Show InChI InChI=1S/C11H11N3O2/c15-10-6-9(13-11(16)14-10)12-7-8-4-2-1-3-5-8/h1-6H,7H2,(H3,12,13,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Biochimica ed Evoluzionistica Curated by ChEMBL					Assay Description Inhibition of catabolic activity of human thymidine phosphorylase				J Med Chem 43: 2601-7 (2000) BindingDB Entry DOI: 10.7270/Q2639P06
					More data for this Ligand-Target Pair