BDBM50022167 2-Amino-6-(indan-5-ylamino)-3H-pyrimidin-4-one::CHEMBL349592

SMILES: Nc1nc(Nc2ccc3CCCc3c2)cc(=O)[nH]1

InChI Key: InChIKey=YUPQFUXJUXRXOG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase III (Bacillus subtilis)	BDBM50022167 (2-Amino-6-(indan-5-ylamino)-3H-pyrimidin-4-one | C...) Show SMILES Nc1nc(Nc2ccc3CCCc3c2)cc(=O)[nH]1 Show InChI InChI=1S/C13H14N4O/c14-13-16-11(7-12(18)17-13)15-10-5-4-8-2-1-3-9(8)6-10/h4-7H,1-3H2,(H4,14,15,16,17,18)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration producing 50% inhibition of Bacillus subtilis DNA topoisomerase III in the presence of dATP using DNA Polymerase assay				J Med Chem 29: 676-81 (1986) BindingDB Entry DOI: 10.7270/Q2MP528D
					More data for this Ligand-Target Pair