BDBM50022260 11,12-Dihydro-3H-1-oxa-benzo[4,5]cyclohepta[1,2-e]indene-2,6-dione::CHEMBL311679

SMILES: O=C1Cc2ccc3c(CCc4ccccc4C3=O)c2O1

InChI Key: InChIKey=AMMUSGBZUXCBIC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50022260 (11,12-Dihydro-3H-1-oxa-benzo[4,5]cyclohepta[1,2-e]...) Show SMILES O=C1Cc2ccc3c(CCc4ccccc4C3=O)c2O1 Show InChI InChI=1S/C17H12O3/c18-15-9-11-6-7-13-14(17(11)20-15)8-5-10-3-1-2-4-12(10)16(13)19/h1-4,6-7H,5,8-9H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rabbit lens aldose reductase.				J Med Chem 29: 2347-51 (1986) BindingDB Entry DOI: 10.7270/Q23R0RWW
					More data for this Ligand-Target Pair