BDBM50022262 2-(4-Hydroxy-5-oxo-5H-dibenzo[a,d]cyclohepten-2-yl)-propionic acid::CHEMBL75630

SMILES: CC(C(O)=O)c1cc(O)c2c(c1)ccc1ccccc1c2=O

InChI Key: InChIKey=CYTFFERWWABCGA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50022262 (2-(4-Hydroxy-5-oxo-5H-dibenzo[a,d]cyclohepten-2-yl...) Show SMILES CC(C(O)=O)c1cc(O)c2c(c1)ccc1ccccc1c2=O Show InChI InChI=1S/C18H14O4/c1-10(18(21)22)13-8-12-7-6-11-4-2-3-5-14(11)17(20)16(12)15(19)9-13/h2-10,19H,1H3,(H,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rabbit lens aldose reductase.				J Med Chem 29: 2347-51 (1986) BindingDB Entry DOI: 10.7270/Q23R0RWW
					More data for this Ligand-Target Pair