BDBM50022267 (6-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-2-yl)-acetic acid::CHEMBL432929

SMILES: OC(=O)Cc1ccc2c(CCc3cccc(O)c3C2=O)c1

InChI Key: InChIKey=VRMDZOJSFRMSSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50022267 ((6-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cycl...) Show SMILES OC(=O)Cc1ccc2c(CCc3cccc(O)c3C2=O)c1 Show InChI InChI=1S/C17H14O4/c18-14-3-1-2-11-5-6-12-8-10(9-15(19)20)4-7-13(12)17(21)16(11)14/h1-4,7-8,18H,5-6,9H2,(H,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rabbit lens aldose reductase.				J Med Chem 29: 2347-51 (1986) BindingDB Entry DOI: 10.7270/Q23R0RWW
					More data for this Ligand-Target Pair