BDBM50022270 (1-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-2-yl)-acetic acid::CHEMBL74436

SMILES: OC(=O)Cc1ccc2c(CCc3ccccc3C2=O)c1O

InChI Key: InChIKey=PQOQARPAPRNBTE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50022270 ((1-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cycl...) Show SMILES OC(=O)Cc1ccc2c(CCc3ccccc3C2=O)c1O Show InChI InChI=1S/C17H14O4/c18-15(19)9-11-6-8-14-13(16(11)20)7-5-10-3-1-2-4-12(10)17(14)21/h1-4,6,8,20H,5,7,9H2,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rabbit lens aldose reductase.				J Med Chem 29: 2347-51 (1986) BindingDB Entry DOI: 10.7270/Q23R0RWW
					More data for this Ligand-Target Pair