BDBM50022546 CHEMBL3297897

SMILES: COc1ccc(Nc2nc(C)nc3oc(C)cc23)cc1

InChI Key: InChIKey=SFTLZKDAWSMUNG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50022546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50022546 (CHEMBL3297897) Show SMILES COc1ccc(Nc2nc(C)nc3oc(C)cc23)cc1 Show InChI InChI=1S/C15H15N3O2/c1-9-8-13-14(16-10(2)17-15(13)20-9)18-11-4-6-12(19-3)7-5-11/h4-8H,1-3H3,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in human U251 cells by phosphotyrosine ELISA assay				Bioorg Med Chem 22: 3753-72 (2014) Article DOI: 10.1016/j.bmc.2014.04.049 BindingDB Entry DOI: 10.7270/Q20K2B45
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50022546 (CHEMBL3297897) Show SMILES COc1ccc(Nc2nc(C)nc3oc(C)cc23)cc1 Show InChI InChI=1S/C15H15N3O2/c1-9-8-13-14(16-10(2)17-15(13)20-9)18-11-4-6-12(19-3)7-5-11/h4-8H,1-3H3,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta in human SH-SY5Y cells by phosphotyrosine ELISA assay				Bioorg Med Chem 22: 3753-72 (2014) Article DOI: 10.1016/j.bmc.2014.04.049 BindingDB Entry DOI: 10.7270/Q20K2B45
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50022546 (CHEMBL3297897) Show SMILES COc1ccc(Nc2nc(C)nc3oc(C)cc23)cc1 Show InChI InChI=1S/C15H15N3O2/c1-9-8-13-14(16-10(2)17-15(13)20-9)18-11-4-6-12(19-3)7-5-11/h4-8H,1-3H3,(H,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of EGFR in human A431 cells by phosphotyrosine ELISA assay				Bioorg Med Chem 22: 3753-72 (2014) Article DOI: 10.1016/j.bmc.2014.04.049 BindingDB Entry DOI: 10.7270/Q20K2B45
					More data for this Ligand-Target Pair