BDBM50022795 3-(3-Bromo-3-fluoro-2-oxo-azetidin-1-yl)-4-methyl-benzoic acid::CHEMBL125652

SMILES: Cc1ccc(cc1N1CC(F)(Br)C1=O)C(O)=O

InChI Key: InChIKey=ZMEYGWYAPROCLD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (TEM-1) (Escherichia coli)	BDBM50022795 (3-(3-Bromo-3-fluoro-2-oxo-azetidin-1-yl)-4-methyl-...) Show SMILES Cc1ccc(cc1N1CC(F)(Br)C1=O)C(O)=O Show InChI InChI=1S/C11H9BrFNO3/c1-6-2-3-7(9(15)16)4-8(6)14-5-11(12,13)10(14)17/h2-4H,5H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-CERCOA Curated by ChEMBL					Assay Description Inhibition constant (Ki) for TEM-1 beta-lactamase				J Med Chem 31: 370-4 (1988) BindingDB Entry DOI: 10.7270/Q21R6PHS
					More data for this Ligand-Target Pair