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BDBM50023296 2-(1-Carboxymethyl-2-oxo-7-phenyl-azepan-3-ylamino)-4-phenyl-butyric acid::CHEMBL335679

SMILES: OC(=O)CN1[C@@H](CCC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1

InChI Key: InChIKey=SXGPIUOPGHUNJL-ACRUOGEOSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023296   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin-converting enzyme


(Oryctolagus cuniculus)		BDBM50023296
PNG
(2-(1-Carboxymethyl-2-oxo-7-phenyl-azepan-3-ylamino...)
Show SMILES OC(=O)CN1[C@@H](CCC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1ccccc1
Show InChI InChI=1S/C24H28N2O5/c27-22(28)16-26-21(18-10-5-2-6-11-18)13-7-12-19(23(26)29)25-20(24(30)31)15-14-17-8-3-1-4-9-17/h1-6,8-11,19-21,25H,7,12-16H2,(H,27,28)(H,30,31)/t19-,20-,21-/m0/s1
MMDB

KEGG

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PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 3.60n/an/an/an/an/an/a



Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrate

J Med Chem 31: 422-8 (1988)


BindingDB Entry DOI: 10.7270/Q2S75GWH
More data for this
Ligand-Target Pair