BDBM50023416 CHEMBL3327325

SMILES: FC(F)Oc1ccc(cc1OCCCCSC1CCOC1=O)C(=O)Nc1c(Cl)cncc1Cl

InChI Key: InChIKey=FBVIQYXJLZDUSS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50023416 (CHEMBL3327325) Show SMILES FC(F)Oc1ccc(cc1OCCCCSC1CCOC1=O)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C21H20Cl2F2N2O5S/c22-13-10-26-11-14(23)18(13)27-19(28)12-3-4-15(32-21(24)25)16(9-12)30-6-1-2-8-33-17-5-7-31-20(17)29/h3-4,9-11,17,21H,1-2,5-8H2,(H,26,27,28)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assay				Bioorg Med Chem Lett 24: 4594-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.016 BindingDB Entry DOI: 10.7270/Q21C1ZFH
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50023416 (CHEMBL3327325) Show SMILES FC(F)Oc1ccc(cc1OCCCCSC1CCOC1=O)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C21H20Cl2F2N2O5S/c22-13-10-26-11-14(23)18(13)27-19(28)12-3-4-15(32-21(24)25)16(9-12)30-6-1-2-8-33-17-5-7-31-20(17)29/h3-4,9-11,17,21H,1-2,5-8H2,(H,26,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assay				Bioorg Med Chem Lett 24: 4594-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.016 BindingDB Entry DOI: 10.7270/Q21C1ZFH
					More data for this Ligand-Target Pair