BDBM50023634 CHEMBL3341886

SMILES: COc1cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc(OC)c1OC

InChI Key: InChIKey=WGHYZMUZGXWEMW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50023634 (CHEMBL3341886) Show SMILES COc1cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc(OC)c1OC Show InChI InChI=1S/C25H28N4O4/c1-31-21-15-19(16-22(32-2)24(21)33-3)27-25(30)26-18-9-6-8-17(14-18)20-10-7-11-23(28-20)29-12-4-5-13-29/h6-11,14-16H,4-5,12-13H2,1-3H3,(H2,26,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...				J Med Chem 57: 7758-69 (2014) Article DOI: 10.1021/jm501042u BindingDB Entry DOI: 10.7270/Q26W9CNX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50023634 (CHEMBL3341886) Show SMILES COc1cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc(OC)c1OC Show InChI InChI=1S/C25H28N4O4/c1-31-21-15-19(16-22(32-2)24(21)33-3)27-25(30)26-18-9-6-8-17(14-18)20-10-7-11-23(28-20)29-12-4-5-13-29/h6-11,14-16H,4-5,12-13H2,1-3H3,(H2,26,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...				J Med Chem 57: 7758-69 (2014) Article DOI: 10.1021/jm501042u BindingDB Entry DOI: 10.7270/Q26W9CNX
					More data for this Ligand-Target Pair