BDBM50023674 CHEMBL3341887

SMILES: Cc1cc(C)cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1

InChI Key: InChIKey=JDRAHOHYDYDSRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50023674 (CHEMBL3341887) Show SMILES Cc1cc(C)cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1 Show InChI InChI=1S/C24H26N4O/c1-17-13-18(2)15-21(14-17)26-24(29)25-20-8-5-7-19(16-20)22-9-6-10-23(27-22)28-11-3-4-12-28/h5-10,13-16H,3-4,11-12H2,1-2H3,(H2,25,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...				J Med Chem 57: 7758-69 (2014) Article DOI: 10.1021/jm501042u BindingDB Entry DOI: 10.7270/Q26W9CNX
					More data for this Ligand-Target Pair