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BDBM50023679 CHEMBL3341891

SMILES: Clc1cccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1

InChI Key: InChIKey=SHJUYVCKURRHSH-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023679   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023679
PNG
(CHEMBL3341891)
Show SMILES Clc1cccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1
Show InChI InChI=1S/C22H21ClN4O/c23-17-7-4-9-19(15-17)25-22(28)24-18-8-3-6-16(14-18)20-10-5-11-21(26-20)27-12-1-2-13-27/h3-11,14-15H,1-2,12-13H2,(H2,24,25,28)
PDB

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Article
PubMed
n/an/a 228n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair