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BDBM50023882 5-(6-Amino-purin-9-yl)-pent-3-ene-1,2-diol::CHEMBL416457

SMILES: Nc1ncnc2n(C\C=C/[C@@H](O)CO)cnc12

InChI Key: InChIKey=SLKRDCRJTPFGNI-TWJVDONLSA-N

Data: 1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023882   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosylhomocysteinase


(Homo sapiens)
BDBM50023882
PNG
(5-(6-Amino-purin-9-yl)-pent-3-ene-1,2-diol | CHEMB...)
Show SMILES Nc1ncnc2n(C\C=C/[C@@H](O)CO)cnc12
Show InChI InChI=1S/C10H13N5O2/c11-9-8-10(13-5-12-9)15(6-14-8)3-1-2-7(17)4-16/h1-2,5-7,16-17H,3-4H2,(H2,11,12,13)/b2-1-/t7-/m1/s1
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PC cid
PC sid
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Similars

PubMed
200n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase


Citation and Details
More data for this
Ligand-Target Pair
Adenosylhomocysteinase


(Mus musculus)
BDBM50023882
PNG
(5-(6-Amino-purin-9-yl)-pent-3-ene-1,2-diol | CHEMB...)
Show SMILES Nc1ncnc2n(C\C=C/[C@@H](O)CO)cnc12
Show InChI InChI=1S/C10H13N5O2/c11-9-8-10(13-5-12-9)15(6-14-8)3-1-2-7(17)4-16/h1-2,5-7,16-17H,3-4H2,(H2,11,12,13)/b2-1-/t7-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Evaluated for the 50% inhibition of S-Adenosyl-homocysteine (AdoHcy) hydrolase L929 lysate from murine L-929 cells


Citation and Details
More data for this
Ligand-Target Pair