BDBM50024095 (R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic acid::CHEMBL349404
SMILES: OC(=O)CC(=O)N[C@H](CS)Cc1ccccc1
InChI Key: InChIKey=REPVVNYZORKKPQ-JTQLQIEISA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM50024095 ((R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic ...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50024095 ((R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Concentration for 50% inhibition of activity of rat kidney enkephalinase | J Med Chem 29: 751-7 (1986) BindingDB Entry DOI: 10.7270/Q2HM57F3 | |||||||||||
More data for this Ligand-Target Pair |