BDBM50024199 CHEMBL3325534

SMILES: Fc1cc(c(F)cc1OC[C@@H]1CCCC[C@H]1c1ccc(Cl)cc1)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=GTYPKNOGSILUOP-HOCLYGCPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50024199 (CHEMBL3325534) Show SMILES Fc1cc(c(F)cc1OC[C@@H]1CCCC[C@H]1c1ccc(Cl)cc1)S(=O)(=O)Nc1ncns1 |r| Show InChI InChI=1S/C21H20ClF2N3O3S2/c22-15-7-5-13(6-8-15)16-4-2-1-3-14(16)11-30-19-9-18(24)20(10-17(19)23)32(28,29)27-21-25-12-26-31-21/h5-10,12,14,16H,1-4,11H2,(H,25,26,27)/t14-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK cells assessed as reduction in sodium current at -60 mV holding potential by PatchXpress platform based w...				Bioorg Med Chem Lett 24: 4397-401 (2014) Article DOI: 10.1016/j.bmcl.2014.08.017 BindingDB Entry DOI: 10.7270/Q2FF3TX9
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50024199 (CHEMBL3325534) Show SMILES Fc1cc(c(F)cc1OC[C@@H]1CCCC[C@H]1c1ccc(Cl)cc1)S(=O)(=O)Nc1ncns1 |r| Show InChI InChI=1S/C21H20ClF2N3O3S2/c22-15-7-5-13(6-8-15)16-4-2-1-3-14(16)11-30-19-9-18(24)20(10-17(19)23)32(28,29)27-21-25-12-26-31-21/h5-10,12,14,16H,1-4,11H2,(H,25,26,27)/t14-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK cells assessed as reduction in sodium current at -60 mV holding potential by PatchXpress platform based w...				Bioorg Med Chem Lett 24: 4397-401 (2014) Article DOI: 10.1016/j.bmcl.2014.08.017 BindingDB Entry DOI: 10.7270/Q2FF3TX9
					More data for this Ligand-Target Pair