null

SMILES: NCCc1c[nH]c2ccccc12

InChI Key: InChIKey=APJYDQYYACXCRM-UHFFFAOYSA-N

PDB links: 12 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 85 hits for monomerid = 50024210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	772	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Medical College Curated by PDSP Ki Database									Ann N Y Acad Sci 861: 140-5 (1998) Article DOI: 10.1111/j.1749-6632.1998.tb10185.x BindingDB Entry DOI: 10.7270/Q2CV4G8J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	772	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Medical College Curated by PDSP Ki Database									Synapse 35: 144-50 (2000) Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<144::AID-SYN7>3.0.CO;2-K BindingDB Entry DOI: 10.7270/Q2ST7NDX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 98: 8966-71 (2001) Article DOI: 10.1073/pnas.151105198 BindingDB Entry DOI: 10.7270/Q2G15ZD5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (BOVINE)	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by PDSP Ki Database									J Neurosci 9: 3482-90 (1989) BindingDB Entry DOI: 10.7270/Q2FX77Z2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (RAT)	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									Neuropharmacology 36: 713-20 (1997) Article DOI: 10.1016/s0028-3908(97)00019-1 BindingDB Entry DOI: 10.7270/Q2MW2FP8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Life Sci 33: 2011-6 (1983) Article DOI: 10.1016/0024-3205(83)90740-3 BindingDB Entry DOI: 10.7270/Q2DR2T0M
					More data for this Ligand-Target Pair
Cytochrome P450 2A6 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Competitive inhibition of CYP2A6 (unknown origin)				Drug Metab Dispos 40: 1797-802 (2012) Article DOI: 10.1124/dmd.112.045161 BindingDB Entry DOI: 10.7270/Q2BK1F3P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 90: 408-12 (1993) Article DOI: 10.1073/pnas.90.2.408 BindingDB Entry DOI: 10.7270/Q2862DZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1E (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP Ki Database									Mol Pharmacol 42: 180-5 (1992) BindingDB Entry DOI: 10.7270/Q2416VJ0
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligand				J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Life Sci 33: 2011-6 (1983) Article DOI: 10.1016/0024-3205(83)90740-3 BindingDB Entry DOI: 10.7270/Q2DR2T0M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP Ki Database									J Pharmacol Exp Ther 265: 1272-9 (1993) BindingDB Entry DOI: 10.7270/Q2833QJ4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP Ki Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (PIG)	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP Ki Database									J Pharmacol Exp Ther 265: 1272-9 (1993) BindingDB Entry DOI: 10.7270/Q2833QJ4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U. 114 Curated by PDSP Ki Database									Nature 305: 140-2 (1983) Article DOI: 10.1038/305140a0 BindingDB Entry DOI: 10.7270/Q2S46QFX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP Ki Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U. 114 Curated by PDSP Ki Database									Nature 305: 140-2 (1983) Article DOI: 10.1038/305140a0 BindingDB Entry DOI: 10.7270/Q2S46QFX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (MOUSE)	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP Ki Database									J Biol Chem 268: 23422-6 (1993) BindingDB Entry DOI: 10.7270/Q28G8J68
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP Ki Database									J Pharmacol Exp Ther 265: 1272-9 (1993) BindingDB Entry DOI: 10.7270/Q2833QJ4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.				J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7
					More data for this Ligand-Target Pair
Cytochrome P450 2A13 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Competitive inhibition of CYP2A13 (unknown origin)				Drug Metab Dispos 40: 1797-802 (2012) Article DOI: 10.1124/dmd.112.045161 BindingDB Entry DOI: 10.7270/Q2BK1F3P
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity at alpha-2 adrenergic receptors of rat.				Bioorg Med Chem Lett 14: 999-1002 (2004) Article DOI: 10.1016/j.bmcl.2003.11.078 BindingDB Entry DOI: 10.7270/Q2SB456G
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIB Swiss Institute of Bioinformatics Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant IDO1 expressed in Escherichia coli BL21 by Lineweaver-Burk double-reciprocal plot analysis				J Med Chem 58: 9421-37 (2015) Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	164	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
					More data for this Ligand-Target Pair
Cytochrome P450 2A6 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Binding affinity to CYP2A6 (unknown origin) assessed as type 2 interaction as increase in absorbance 431 to 432 nm and decrease in 406 to 412 nm				Drug Metab Dispos 40: 1797-802 (2012) Article DOI: 10.1124/dmd.112.045161 BindingDB Entry DOI: 10.7270/Q2BK1F3P
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Cytochrome P450 2A13 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Binding affinity to CYP2A13 (unknown origin) assessed as type 2 interaction as increase in absorbance 431 to 432 nm and decrease in 406 to 412 nm				Drug Metab Dispos 40: 1797-802 (2012) Article DOI: 10.1124/dmd.112.045161 BindingDB Entry DOI: 10.7270/Q2BK1F3P
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Transporter (Rattus norvegicus)	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	716	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
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Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
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5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
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5-hydroxytryptamine receptor 2B (RAT)	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	537	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundus				J Med Chem 25: 68-70 (1982) BindingDB Entry DOI: 10.7270/Q2902507
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Cathepsin K (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of cathepsin K (unknown origin) by fluorimetric assay				J Nat Prod 65: 628-9 (2002) BindingDB Entry DOI: 10.7270/Q2B27V1V
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Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Agonist activity at rat N-terminal FLAG-tagged TAAR1 expressed in HEK293 cells assessed as [3H]cAMP accumulation measured after 1 hr				J Med Chem 60: 2605-2628 (2017) Article DOI: 10.1021/acs.jmedchem.7b00085 BindingDB Entry DOI: 10.7270/Q2DJ5HWM
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
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Myeloperoxidase (Homo sapiens (Human))	BDBM50024210 (1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...) Show SMILES NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay				J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T
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