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BDBM50024446 (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid hydroxyamide::CHEMBL277123::Icosa-5,8,11,14-tetraenoic acid hydroxyamide(Arachidonohydroxamic acid)

SMILES: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NO

InChI Key: InChIKey=DWUNPFBWVHLUMP-DOFZRALJSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024446   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50024446
PNG
((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid hy...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NO
Show InChI InChI=1S/C20H33NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(22)21-23/h6-7,9-10,12-13,15-16,23H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
PDB

Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Hebrew University

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined against rat brain Cannabinoid receptor 1


J Med Chem 40: 659-67 (1997)


Article DOI: 10.1021/jm960752x
BindingDB Entry DOI: 10.7270/Q2JS9R3C
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50024446
PNG
((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid hy...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NO
Show InChI InChI=1S/C20H33NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(22)21-23/h6-7,9-10,12-13,15-16,23H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.


J Med Chem 30: 1177-86 (1987)


BindingDB Entry DOI: 10.7270/Q25M668Q
More data for this
Ligand-Target Pair