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BDBM50024542 CHEMBL3334991

SMILES: O[C@H]1C[C@H](C1)NC(=O)c1ccc(cn1)C#Cc1cccc(F)c1

InChI Key: InChIKey=UEMINSPNEHIVQD-IYBDPMFKNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024542   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1/M5 chimeric protein


(Homo sapiens)
BDBM50024542
PNG
(CHEMBL3334991)
Show SMILES O[C@H]1C[C@H](C1)NC(=O)c1ccc(cn1)C#Cc1cccc(F)c1
Show InChI InChI=1/C18H15FN2O2/c19-14-3-1-2-12(8-14)4-5-13-6-7-17(20-11-13)18(23)21-15-9-16(22)10-15/h1-3,6-8,11,15-16,22H,9-10H2,(H,21,23)/t15-,16+
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Similars

Article
PubMed
n/an/an/an/a 33n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human muscarinic acetylcholine receptor M5 expressed in CHO cells by fluorometric imaging plate reader


J Med Chem 57: 7485-98 (2014)

More data for this
Ligand-Target Pair