BDBM50024716 CHEMBL3342607

SMILES: Cc1nc2ccc(cc2c(=O)n1-c1cccc(OC(F)(F)F)c1)C(=O)c1cnn(C)c1O

InChI Key: InChIKey=PSILVOHHEPGVGB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50024716 (CHEMBL3342607) Show SMILES Cc1nc2ccc(cc2c(=O)n1-c1cccc(OC(F)(F)F)c1)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C21H15F3N4O4/c1-11-26-17-7-6-12(18(29)16-10-25-27(2)19(16)30)8-15(17)20(31)28(11)13-4-3-5-14(9-13)32-21(22,23)24/h3-10,30H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...				Bioorg Med Chem 22: 5194-211 (2014) Article DOI: 10.1016/j.bmc.2014.08.011 BindingDB Entry DOI: 10.7270/Q2DF6SRG
					More data for this Ligand-Target Pair