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BDBM50024738 CHEMBL3342421

SMILES: COc1ccc(cc1)-n1c(C)nc2ccc(cc2c1=O)C(=O)c1c(C)nn(C)c1O

InChI Key: InChIKey=ZXSWLJADRKCNGB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024738   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens (Human))		BDBM50024738
PNG
(CHEMBL3342421)
Show SMILES COc1ccc(cc1)-n1c(C)nc2ccc(cc2c1=O)C(=O)c1c(C)nn(C)c1O
Show InChI InChI=1S/C22H20N4O4/c1-12-19(22(29)25(3)24-12)20(27)14-5-10-18-17(11-14)21(28)26(13(2)23-18)15-6-8-16(30-4)9-7-15/h5-11,29H,1-4H3
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PC cid
PC sid
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Similars
Article
PubMed
 238n/an/an/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...

Bioorg Med Chem 22: 5194-211 (2014)


Article DOI: 10.1016/j.bmc.2014.08.011
BindingDB Entry DOI: 10.7270/Q2DF6SRG
More data for this
Ligand-Target Pair