BDBM50025004 CHEMBL3143467::CHEMBL412481::p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A)

SMILES: Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(=O)O[C@@H]5[C@H](O)[C@@H](CO)O[C@H]5n5c(Br)nc6c(N)ncnc56)O[C@H]4n4c(Br)nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(Br)nc12

InChI Key: InChIKey=ZONIXOUJZOBPJG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50025004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNase L (Mus musculus)	BDBM50025004 (CHEMBL3143467 | p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p...) Show SMILES Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(=O)O[C@@H]5[C@H](O)[C@@H](CO)O[C@H]5n5c(Br)nc6c(N)ncnc56)O[C@H]4n4c(Br)nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(Br)nc12 |r| Show InChI InChI=1S/C50H57Br5N25O26P5/c51-46-71-27-32(56)61-11-66-37(27)76(46)26-5-20(81)25(102-26)10-97-111(91,92)106-24-4-19(101-45(24)80-41-31(75-50(80)55)36(60)65-15-70-41)9-96-110(89,90)105-23-3-18(100-44(23)79-40-30(74-49(79)54)35(59)64-14-69-40)8-95-109(87,88)104-22-2-17(99-43(22)78-39-29(73-48(78)53)34(58)63-13-68-39)7-94-108(85,86)103-21-1-16(6-93-107(82,83)84)98-42(21)77-38-28(72-47(77)52)33(57)62-12-67-38/h11-26,42-45,81H,1-10H2,(H,85,86)(H,87,88)(H,89,90)(H,91,92)(H2,56,61,66)(H2,57,62,67)(H2,58,63,68)(H2,59,64,69)(H2,60,65,70)(H2,82,83,84)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extracts				J Med Chem 29: 1015-22 (1986) BindingDB Entry DOI: 10.7270/Q2SX6C6K
					More data for this Ligand-Target Pair