BDBM50025026 CHEMBL3337847

SMILES: COc1cncc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1

InChI Key: InChIKey=HXESGMYSKDHCFX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50025026 (CHEMBL3337847) Show SMILES COc1cncc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C15H10F2N4O4/c1-23-8-2-7(5-18-6-8)13(22)21-14-19-9-3-11-12(4-10(9)20-14)25-15(16,17)24-11/h2-6H,1H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of human recombinant CK1epsilon expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I delta (Rattus norvegicus (rat))	BDBM50025026 (CHEMBL3337847) Show SMILES COc1cncc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C15H10F2N4O4/c1-23-8-2-7(5-18-6-8)13(22)21-14-19-9-3-11-12(4-10(9)20-14)25-15(16,17)24-11/h2-6H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I delta (Rattus norvegicus (rat))	BDBM50025026 (CHEMBL3337847) Show SMILES COc1cncc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C15H10F2N4O4/c1-23-8-2-7(5-18-6-8)13(22)21-14-19-9-3-11-12(4-10(9)20-14)25-15(16,17)24-11/h2-6H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair