BDBM50025464 1-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-[1,3]diazepan-2-one::CHEMBL2367576
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCCCNC1=O
InChI Key: InChIKey=XFBDBFJTEFLACS-FNCVBFRFSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytidine deaminase (Mus musculus) | BDBM50025464 (1-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested in vivo for its ability to inhibit mouse kidney cytidine deaminase (CDA) | J Med Chem 29: 2351-8 (1986) BindingDB Entry DOI: 10.7270/Q2GH9GZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytidine deaminase (Mus musculus) | BDBM50025464 (1-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against cytidine deaminase of mouse kidney | J Med Chem 24: 662-6 (1981) BindingDB Entry DOI: 10.7270/Q2JM2B6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytidine deaminase (Homo sapiens (Human)) | BDBM50025464 (1-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against cytidine deaminase of human liver | J Med Chem 24: 662-6 (1981) BindingDB Entry DOI: 10.7270/Q2JM2B6C | |||||||||||
More data for this Ligand-Target Pair |