BDBM50025580 1,3,7-Tripropyl-3,7-dihydro-purine-2,6-dione::CHEMBL417834
SMILES: CCCn1cnc2n(CCC)c(=O)n(CCC)c(=O)c12
InChI Key: InChIKey=PMJKNRZFAZJNRA-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine A2a receptor (GUINEA PIG) | BDBM50025580 (1,3,7-Tripropyl-3,7-dihydro-purine-2,6-dione | CHE...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its ability to antagonise cyclic [3H]-AMP accumulation in [3H]-adenine-labeled guinea pig cerebral cortical slices. | J Med Chem 29: 1305-8 (1987) BindingDB Entry DOI: 10.7270/Q23777QX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50025580 (1,3,7-Tripropyl-3,7-dihydro-purine-2,6-dione | CHE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Ability to inhibit binding of 1 nM [3H]-cyclohexyladenosine to adenosine A1 receptor in rat cerebral cortical membranes | J Med Chem 29: 1305-8 (1987) BindingDB Entry DOI: 10.7270/Q23777QX | |||||||||||
More data for this Ligand-Target Pair |