BDBM50025916 CHEMBL3335225

SMILES: Oc1ccc(Br)cc1\C=N\c1ccc2[nH]c(=O)[nH]c2c1

InChI Key: InChIKey=ZVAZYZFTSFSLNW-FRKPEAEDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50025916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BRK (Homo sapiens (Human))	BDBM50025916 (CHEMBL3335225) Show SMILES Oc1ccc(Br)cc1\C=N\c1ccc2[nH]c(=O)[nH]c2c1 Show InChI InChI=1S/C14H10BrN3O2/c15-9-1-4-13(19)8(5-9)7-16-10-2-3-11-12(6-10)18-14(20)17-11/h1-7,19H,(H2,17,18,20)/b16-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of GST-tagged PTK6 (unknown origin) assessed as phosphorylated tyrosines after 20 mins by ELISA				Bioorg Med Chem Lett 24: 4659-63 (2014) Article DOI: 10.1016/j.bmcl.2014.08.036 BindingDB Entry DOI: 10.7270/Q2TH8P84
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BRK (Homo sapiens (Human))	BDBM50025916 (CHEMBL3335225) Show SMILES Oc1ccc(Br)cc1\C=N\c1ccc2[nH]c(=O)[nH]c2c1 Show InChI InChI=1S/C14H10BrN3O2/c15-9-1-4-13(19)8(5-9)7-16-10-2-3-11-12(6-10)18-14(20)17-11/h1-7,19H,(H2,17,18,20)/b16-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assay				Bioorg Med Chem Lett 24: 4659-63 (2014) Article DOI: 10.1016/j.bmcl.2014.08.036 BindingDB Entry DOI: 10.7270/Q2TH8P84
					More data for this Ligand-Target Pair