BDBM50026250 CHEMBL3358470

SMILES: CN(CCOc1ccccc1C(F)(F)F)C(=O)Nc1ccccc1C(O)=O

InChI Key: InChIKey=OHPJJMHYSRRCBK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50026250 (CHEMBL3358470) Show SMILES CN(CCOc1ccccc1C(F)(F)F)C(=O)Nc1ccccc1C(O)=O Show InChI InChI=1S/C18H17F3N2O4/c1-23(17(26)22-14-8-4-2-6-12(14)16(24)25)10-11-27-15-9-5-3-7-13(15)18(19,20)21/h2-9H,10-11H2,1H3,(H,22,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Displacement of [3H]retinol from biotinylated human RBP4 by scintillation proximity assay				J Med Chem 57: 7731-57 (2014) Article DOI: 10.1021/jm5010013 BindingDB Entry DOI: 10.7270/Q2FB54JT
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50026250 (CHEMBL3358470) Show SMILES CN(CCOc1ccccc1C(F)(F)F)C(=O)Nc1ccccc1C(O)=O Show InChI InChI=1S/C18H17F3N2O4/c1-23(17(26)22-14-8-4-2-6-12(14)16(24)25)10-11-27-15-9-5-3-7-13(15)18(19,20)21/h2-9H,10-11H2,1H3,(H,22,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Antagonist activity at maltose binding protein-tagged RBP4 (unknown origin) expressed in Escherichia coli assessed as inhibition of retinol-induced p...				J Med Chem 57: 7731-57 (2014) Article DOI: 10.1021/jm5010013 BindingDB Entry DOI: 10.7270/Q2FB54JT
					More data for this Ligand-Target Pair