BDBM50026453 CHEMBL3335280

SMILES: ONC(=O)CCCCc1cccn1Cc1cccc(c1)-c1ccccc1

InChI Key: InChIKey=HVTRBOFCGKSVKW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50026453 (CHEMBL3335280) Show SMILES ONC(=O)CCCCc1cccn1Cc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C22H24N2O2/c25-22(23-26)14-5-4-12-21-13-7-15-24(21)17-18-8-6-11-20(16-18)19-9-2-1-3-10-19/h1-3,6-11,13,15-16,26H,4-5,12,14,17H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 after 60 mins by fluorimetric assay				Eur J Med Chem 86: 639-52 (2014) Article DOI: 10.1016/j.ejmech.2014.09.024 BindingDB Entry DOI: 10.7270/Q2NV9KTB
					More data for this Ligand-Target Pair