BDBM50026629 CHEMBL3334509

SMILES: ONC(=O)CCCCCCNC(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc(O)cc(O)c1

InChI Key: InChIKey=WGXIHKKEQXGZPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50026629 (CHEMBL3334509) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc(O)cc(O)c1 Show InChI InChI=1S/C26H28N2O5/c29-23-15-22(16-24(30)17-23)20-8-6-18(7-9-20)19-10-12-21(13-11-19)26(32)27-14-4-2-1-3-5-25(31)28-33/h6-13,15-17,29-30,33H,1-5,14H2,(H,27,32)(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assay				ACS Med Chem Lett 5: 973-8 (2014) Article DOI: 10.1021/ml5000959 BindingDB Entry DOI: 10.7270/Q2125V70
					More data for this Ligand-Target Pair