BDBM50026671 1-(4,5-Dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-4-hydroxy-1H-pyrimidin-2-one::CHEMBL1966557

SMILES: OCC1=C[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O

InChI Key: InChIKey=FCWVOJUKQSHZIV-VDAHYXPESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho/Rac guanine nucleotide exchange factor (Homo sapiens (Human))	BDBM50026671 (1-(4,5-Dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)...) Show SMILES OCC1=C[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |t:2| Show InChI InChI=1S/C10H12N2O5/c13-4-5-3-6(9(16)8(5)15)12-2-1-7(14)11-10(12)17/h1-3,6,8-9,13,15-16H,4H2,(H,11,14,17)/t6-,8-,9+/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to uridine kinase from L1210. was determined from the dixon plot				J Med Chem 27: 1536-8 (1985) BindingDB Entry DOI: 10.7270/Q2FF3RC9
					More data for this Ligand-Target Pair