BDBM50026839 CHEMBL1957087

SMILES: FC(F)(F)c1ccc(cc1)-c1ocnc1C(=O)NCc1ccncc1

InChI Key: InChIKey=OYNSGYVBIINFBB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026839 (CHEMBL1957087) Show SMILES FC(F)(F)c1ccc(cc1)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H12F3N3O2/c18-17(19,20)13-3-1-12(2-4-13)15-14(23-10-25-15)16(24)22-9-11-5-7-21-8-6-11/h1-8,10H,9H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GSK3-beta by fluorescence polarization assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair