BDBM50026873 CHEMBL542296

SMILES: Cl.COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(c2)-n2nc(-c3cccnc3)c3ccccc3c2=O)c1C(=O)OC

InChI Key: InChIKey=BKJRZFQJTHYCRM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026873   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50026873 (CHEMBL542296) Show SMILES Cl.COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(c2)-n2nc(-c3cccnc3)c3ccccc3c2=O)c1C(=O)OC Show InChI InChI=1S/C34H26N4O7.ClH/c1-42-26-15-21-14-25(33(40)44-3)30(34(41)45-4)29(24(21)17-27(26)43-2)19-11-13-36-28(16-19)38-32(39)23-10-6-5-9-22(23)31(37-38)20-8-7-12-35-18-20;/h5-18H,1-4H3;1H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricle				J Med Chem 42: 1088-99 (1999) Article DOI: 10.1021/jm980314l BindingDB Entry DOI: 10.7270/Q25M66DH
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50026873 (CHEMBL542296) Show SMILES Cl.COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(c2)-n2nc(-c3cccnc3)c3ccccc3c2=O)c1C(=O)OC Show InChI InChI=1S/C34H26N4O7.ClH/c1-42-26-15-21-14-25(33(40)44-3)30(34(41)45-4)29(24(21)17-27(26)43-2)19-11-13-36-28(16-19)38-32(39)23-10-6-5-9-22(23)31(37-38)20-8-7-12-35-18-20;/h5-18H,1-4H3;1H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of Phosphodiesterase 4 from guinea pig lung				J Med Chem 42: 1088-99 (1999) Article DOI: 10.1021/jm980314l BindingDB Entry DOI: 10.7270/Q25M66DH
					More data for this Ligand-Target Pair