BDBM50026874 CHEMBL556787

SMILES: Cl.COc1cc2cc(COC(C)=O)c(COC(C)=O)c(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c2cc1OC

InChI Key: InChIKey=IMSSXFSSNBNULA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50026874 (CHEMBL556787) Show SMILES Cl.COc1cc2cc(COC(C)=O)c(COC(C)=O)c(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c2cc1OC Show InChI InChI=1S/C36H30N4O7.ClH/c1-21(41)46-19-26-14-25-15-31(44-3)32(45-4)17-29(25)34(30(26)20-47-22(2)42)23-11-13-38-33(16-23)40-36(43)28-10-6-5-9-27(28)35(39-40)24-8-7-12-37-18-24;/h5-18H,19-20H2,1-4H3;1H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of Phosphodiesterase 4 from guinea pig lung				J Med Chem 42: 1088-99 (1999) Article DOI: 10.1021/jm980314l BindingDB Entry DOI: 10.7270/Q25M66DH
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50026874 (CHEMBL556787) Show SMILES Cl.COc1cc2cc(COC(C)=O)c(COC(C)=O)c(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c2cc1OC Show InChI InChI=1S/C36H30N4O7.ClH/c1-21(41)46-19-26-14-25-15-31(44-3)32(45-4)17-29(25)34(30(26)20-47-22(2)42)23-11-13-38-33(16-23)40-36(43)28-10-6-5-9-27(28)35(39-40)24-8-7-12-37-18-24;/h5-18H,19-20H2,1-4H3;1H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricle				J Med Chem 42: 1088-99 (1999) Article DOI: 10.1021/jm980314l BindingDB Entry DOI: 10.7270/Q25M66DH
					More data for this Ligand-Target Pair