BDBM50026879 CHEMBL543491

SMILES: Cl.Cl.COc1cc2c(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c(CO)c(CO)cc2cc1OCc1ccccc1

InChI Key: InChIKey=RVKKSTDMZDAERR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50026879 (CHEMBL543491) Show SMILES Cl.Cl.COc1cc2c(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c(CO)c(CO)cc2cc1OCc1ccccc1 Show InChI InChI=1S/C38H30N4O5.2ClH/c1-46-33-19-31-27(17-34(33)47-23-24-8-3-2-4-9-24)16-28(21-43)32(22-44)36(31)25-13-15-40-35(18-25)42-38(45)30-12-6-5-11-29(30)37(41-42)26-10-7-14-39-20-26;;/h2-20,43-44H,21-23H2,1H3;2*1H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of guinea pig cardiac ventricle Phosphodiesterase 3				J Med Chem 42: 1088-99 (1999) Article DOI: 10.1021/jm980314l BindingDB Entry DOI: 10.7270/Q25M66DH
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50026879 (CHEMBL543491) Show SMILES Cl.Cl.COc1cc2c(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c(CO)c(CO)cc2cc1OCc1ccccc1 Show InChI InChI=1S/C38H30N4O5.2ClH/c1-46-33-19-31-27(17-34(33)47-23-24-8-3-2-4-9-24)16-28(21-43)32(22-44)36(31)25-13-15-40-35(18-25)42-38(45)30-12-6-5-11-29(30)37(41-42)26-10-7-14-39-20-26;;/h2-20,43-44H,21-23H2,1H3;2*1H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of Phosphodiesterase 4 from guinea pig lung				J Med Chem 42: 1088-99 (1999) Article DOI: 10.1021/jm980314l BindingDB Entry DOI: 10.7270/Q25M66DH
					More data for this Ligand-Target Pair