BDBM50026972 11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrrolo[1,2-a]azepine::CHEMBL175154
SMILES: [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2cccn2-[#6]=[#6]-c2ccccc-12
InChI Key: InChIKey=PLDCWFRDWHUWHR-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...) | BDBM50026972 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortex | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor (RAT) | BDBM50026972 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- QNB binding at the muscarinic-cholinergic binding site of rat brain S1 | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cerebral cortex alpha adrenergic receptor (CALF) | BDBM50026972 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- prazosin radioligand binding at the alpha 1-adrenergic binding site of calf cerebral cortex | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50026972 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudate | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50026972 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudate | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
adrenergic Alpha2 (BOVINE) | BDBM50026972 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB KEGG GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 226 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- clonidine radioligand binding at the alpha-2 adrenergic receptor binding site of calf cerebral cortex | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair |