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BDBM50027024 1-(3-Fluoro-pyridin-2-yl)-piperazine::CHEMBL48833::L-644,763

SMILES: Fc1cccnc1N1CCNCC1

InChI Key: InChIKey=HPYRNHPSWLCJKD-UHFFFAOYSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50027024
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2A adrenergic receptor (BOVINE)	BDBM50027024 (1-(3-Fluoro-pyridin-2-yl)-piperazine \| CHEMBL48833...) Show SMILES Fc1cccnc1N1CCNCC1 Show InChI	PDB KEGG GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligand				J Med Chem 26: 1696-701 (1984) BindingDB Entry DOI: 10.7270/Q2251H67
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50027024 (1-(3-Fluoro-pyridin-2-yl)-piperazine \| CHEMBL48833...) Show SMILES Fc1cccnc1N1CCNCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (OK)	BDBM50027024 (1-(3-Fluoro-pyridin-2-yl)-piperazine \| CHEMBL48833...) Show SMILES Fc1cccnc1N1CCNCC1 Show InChI	GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (NEONATAL RAT)	BDBM50027024 (1-(3-Fluoro-pyridin-2-yl)-piperazine \| CHEMBL48833...) Show SMILES Fc1cccnc1N1CCNCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM50027024 (1-(3-Fluoro-pyridin-2-yl)-piperazine \| CHEMBL48833...) Show SMILES Fc1cccnc1N1CCNCC1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding activity against alpha-1 adrenergic receptor from calf cerebral cortex, using [3H]-prazosin as the radioligand				J Med Chem 26: 1696-701 (1984) BindingDB Entry DOI: 10.7270/Q2251H67
TBA Curated by ChEMBL					More data for this Ligand-Target Pair