Found 6 hits for monomerid = 50027242 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50027242
(CHEMBL2113308)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3O |THB:10:9:5.4.6:14| Show InChI InChI=1S/C30H33N3O6/c1-32-14-13-29-25-19-6-9-22(34)26(25)39-27(29)30(38-2)12-11-28(29,23(32)15-19)16-20(30)17-31-24(35)10-5-18-3-7-21(8-4-18)33(36)37/h3-10,20,23,27,34H,11-17H2,1-2H3,(H,31,35)/b10-5+/t20-,23-,27-,28-,29+,30+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from human cloned mu opioid receptor |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50027242
(CHEMBL2113308)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3O |THB:10:9:5.4.6:14| Show InChI InChI=1S/C30H33N3O6/c1-32-14-13-29-25-19-6-9-22(34)26(25)39-27(29)30(38-2)12-11-28(29,23(32)15-19)16-20(30)17-31-24(35)10-5-18-3-7-21(8-4-18)33(36)37/h3-10,20,23,27,34H,11-17H2,1-2H3,(H,31,35)/b10-5+/t20-,23-,27-,28-,29+,30+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from human cloned kappa opioid receptor |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50027242
(CHEMBL2113308)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3O |THB:10:9:5.4.6:14| Show InChI InChI=1S/C30H33N3O6/c1-32-14-13-29-25-19-6-9-22(34)26(25)39-27(29)30(38-2)12-11-28(29,23(32)15-19)16-20(30)17-31-24(35)10-5-18-3-7-21(8-4-18)33(36)37/h3-10,20,23,27,34H,11-17H2,1-2H3,(H,31,35)/b10-5+/t20-,23-,27-,28-,29+,30+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from human cloned delta opioid receptor |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50027242
(CHEMBL2113308)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3O |THB:10:9:5.4.6:14| Show InChI InChI=1S/C30H33N3O6/c1-32-14-13-29-25-19-6-9-22(34)26(25)39-27(29)30(38-2)12-11-28(29,23(32)15-19)16-20(30)17-31-24(35)10-5-18-3-7-21(8-4-18)33(36)37/h3-10,20,23,27,34H,11-17H2,1-2H3,(H,31,35)/b10-5+/t20-,23-,27-,28-,29+,30+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50027242
(CHEMBL2113308)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3O |THB:10:9:5.4.6:14| Show InChI InChI=1S/C30H33N3O6/c1-32-14-13-29-25-19-6-9-22(34)26(25)39-27(29)30(38-2)12-11-28(29,23(32)15-19)16-20(30)17-31-24(35)10-5-18-3-7-21(8-4-18)33(36)37/h3-10,20,23,27,34H,11-17H2,1-2H3,(H,31,35)/b10-5+/t20-,23-,27-,28-,29+,30+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50027242
(CHEMBL2113308)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3O |THB:10:9:5.4.6:14| Show InChI InChI=1S/C30H33N3O6/c1-32-14-13-29-25-19-6-9-22(34)26(25)39-27(29)30(38-2)12-11-28(29,23(32)15-19)16-20(30)17-31-24(35)10-5-18-3-7-21(8-4-18)33(36)37/h3-10,20,23,27,34H,11-17H2,1-2H3,(H,31,35)/b10-5+/t20-,23-,27-,28-,29+,30+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
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