BDBM50027306 1H-Indole-5-carboxamidine::CHEMBL26490

SMILES: NC(=N)c1ccc2[nH]ccc2c1

InChI Key: InChIKey=DAUPWONEWDTPEP-UHFFFAOYSA-N

Data: 5 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50027306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombin (Bos taurus (Bovine))	BDBM50027306 (1H-Indole-5-carboxamidine | CHEMBL26490) Show SMILES NC(=N)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C9H9N3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,12H,(H3,10,11)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against bovine thrombin				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50027306 (1H-Indole-5-carboxamidine | CHEMBL26490) Show SMILES NC(=N)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C9H9N3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,12H,(H3,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against bovine trypsin				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50027306 (1H-Indole-5-carboxamidine | CHEMBL26490) Show SMILES NC(=N)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C9H9N3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,12H,(H3,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against human plasminogen				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50027306 (1H-Indole-5-carboxamidine | CHEMBL26490) Show SMILES NC(=N)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C9H9N3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,12H,(H3,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Urokinase				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair
Hepsin (Homo sapiens (Human))	BDBM50027306 (1H-Indole-5-carboxamidine | CHEMBL26490) Show SMILES NC(=N)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C9H9N3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,12H,(H3,10,11)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50027306 (1H-Indole-5-carboxamidine | CHEMBL26490) Show SMILES NC(=N)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C9H9N3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,12H,(H3,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of human alpha-thrombin catalytic activity.				Bioorg Med Chem Lett 6: 1339-1344 (1996) Article DOI: 10.1016/0960-894X(96)00229-6 BindingDB Entry DOI: 10.7270/Q2TM7B2Z
					More data for this Ligand-Target Pair