BDBM50027388 CHEMBL591898

SMILES: CC(C)(C)C(=O)N1Cc2c(NC(=O)C3CCNCC3)n[nH]c2C1(C)C

InChI Key: InChIKey=ZCQQEWOROAMZJH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50027388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027388 (CHEMBL591898) Show SMILES CC(C)(C)C(=O)N1Cc2c(NC(=O)C3CCNCC3)n[nH]c2C1(C)C Show InChI InChI=1S/C18H29N5O2/c1-17(2,3)16(25)23-10-12-13(18(23,4)5)21-22-14(12)20-15(24)11-6-8-19-9-7-11/h11,19H,6-10H2,1-5H3,(H2,20,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair