BDBM50027389 CHEMBL599033

SMILES: CN1CCC(CC1)C(=O)Nc1n[nH]c2c1CN(C(=O)C(C)(C)C)C2(C)C

InChI Key: InChIKey=DHJHGYYBWIWMJK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50027389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027389 (CHEMBL599033) Show SMILES CN1CCC(CC1)C(=O)Nc1n[nH]c2c1CN(C(=O)C(C)(C)C)C2(C)C Show InChI InChI=1S/C19H31N5O2/c1-18(2,3)17(26)24-11-13-14(19(24,4)5)21-22-15(13)20-16(25)12-7-9-23(6)10-8-12/h12H,7-11H2,1-6H3,(H2,20,21,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair