Found 5 hits for monomerid = 50027391 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50027391
(Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-di...)Show SMILES CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H31NO2/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16,18,22H,6,17H2,1-5H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Patents
Similars
| PubMed
| 9.86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 274: 1263-70 (1995)
BindingDB Entry DOI: 10.7270/Q2R20ZVX |
More data for this Ligand-Target Pair | |
Opioid receptors; mu & delta
(Rattus norvegicus (rat)) | BDBM50027391
(Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-di...)Show SMILES CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H31NO2/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16,18,22H,6,17H2,1-5H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Patents
Similars
| PubMed
| 169 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 274: 1263-70 (1995)
BindingDB Entry DOI: 10.7270/Q2R20ZVX |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50027391
(Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-di...)Show SMILES CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H31NO2/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16,18,22H,6,17H2,1-5H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Patents
Similars
| PubMed
| 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 274: 1263-70 (1995)
BindingDB Entry DOI: 10.7270/Q2R20ZVX |
More data for this Ligand-Target Pair | |
Norepinephrine transporter
(RAT) | BDBM50027391
(Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-di...)Show SMILES CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H31NO2/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16,18,22H,6,17H2,1-5H3 | GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Patents
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 274: 1263-70 (1995)
BindingDB Entry DOI: 10.7270/Q2R20ZVX |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50027391
(Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-di...)Show SMILES CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H31NO2/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16,18,22H,6,17H2,1-5H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Reverse proteomics research institute
Curated by ChEMBL
| Assay Description Inhibitory concentration against potassium channel HERG |
Bioorg Med Chem Lett 15: 2886-90 (2005)
Article DOI: 10.1016/j.bmcl.2005.03.080 BindingDB Entry DOI: 10.7270/Q29S1S7C |
More data for this Ligand-Target Pair | |