BDBM50027489 CHEMBL3335597

SMILES: COc1ccc(\C=C\C(=O)c2ccc(O)cc2C)c(OC)c1OC

InChI Key: InChIKey=WYADPPPAHTYQNX-WEVVVXLNSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50027489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human))	BDBM50027489 (CHEMBL3335597) Show SMILES COc1ccc(\C=C\C(=O)c2ccc(O)cc2C)c(OC)c1OC Show InChI InChI=1S/C19H20O5/c1-12-11-14(20)7-8-15(12)16(21)9-5-13-6-10-17(22-2)19(24-4)18(13)23-3/h5-11,20H,1-4H3/b9-5+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...				Eur J Med Chem 86: 724-39 (2014) Article DOI: 10.1016/j.ejmech.2014.09.039 BindingDB Entry DOI: 10.7270/Q2PN977T
					More data for this Ligand-Target Pair