null

SMILES: SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1

InChI Key: InChIKey=NEGLYSNZRMUEHF-ZEQRLZLVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50027595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50027595 (CHEMBL3356935) Show SMILES SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C27H35N3O4S/c31-25-15-8-14-24(29-25)27(33)30-23(13-5-2-6-16-35)26(32)28-18-21-11-7-12-22(17-21)34-19-20-9-3-1-4-10-20/h1,3-4,7,9-12,17,23-24,35H,2,5-6,8,13-16,18-19H2,(H,28,32)(H,29,31)(H,30,33)/t23-,24-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	495	n/a	n/a	n/a	n/a	n/a	n/a
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay				J Med Chem 57: 8358-77 (2014) Article DOI: 10.1021/jm5008209 BindingDB Entry DOI: 10.7270/Q2JW8GGN
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50027595 (CHEMBL3356935) Show SMILES SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C27H35N3O4S/c31-25-15-8-14-24(29-25)27(33)30-23(13-5-2-6-16-35)26(32)28-18-21-11-7-12-22(17-21)34-19-20-9-3-1-4-10-20/h1,3-4,7,9-12,17,23-24,35H,2,5-6,8,13-16,18-19H2,(H,28,32)(H,29,31)(H,30,33)/t23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay				J Med Chem 57: 8358-77 (2014) Article DOI: 10.1021/jm5008209 BindingDB Entry DOI: 10.7270/Q2JW8GGN
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50027595 (CHEMBL3356935) Show SMILES SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C27H35N3O4S/c31-25-15-8-14-24(29-25)27(33)30-23(13-5-2-6-16-35)26(32)28-18-21-11-7-12-22(17-21)34-19-20-9-3-1-4-10-20/h1,3-4,7,9-12,17,23-24,35H,2,5-6,8,13-16,18-19H2,(H,28,32)(H,29,31)(H,30,33)/t23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using fluorogenic tetrapeptide RHK(Ac)K(Ac) substrate by fluorescence assay				J Med Chem 57: 8358-77 (2014) Article DOI: 10.1021/jm5008209 BindingDB Entry DOI: 10.7270/Q2JW8GGN
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50027595 (CHEMBL3356935) Show SMILES SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C27H35N3O4S/c31-25-15-8-14-24(29-25)27(33)30-23(13-5-2-6-16-35)26(32)28-18-21-11-7-12-22(17-21)34-19-20-9-3-1-4-10-20/h1,3-4,7,9-12,17,23-24,35H,2,5-6,8,13-16,18-19H2,(H,28,32)(H,29,31)(H,30,33)/t23-,24-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA Curated by ChEMBL					Assay Description Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay				J Med Chem 57: 8358-77 (2014) Article DOI: 10.1021/jm5008209 BindingDB Entry DOI: 10.7270/Q2JW8GGN
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50027595 (CHEMBL3356935) Show SMILES SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C27H35N3O4S/c31-25-15-8-14-24(29-25)27(33)30-23(13-5-2-6-16-35)26(32)28-18-21-11-7-12-22(17-21)34-19-20-9-3-1-4-10-20/h1,3-4,7,9-12,17,23-24,35H,2,5-6,8,13-16,18-19H2,(H,28,32)(H,29,31)(H,30,33)/t23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay				J Med Chem 57: 8358-77 (2014) Article DOI: 10.1021/jm5008209 BindingDB Entry DOI: 10.7270/Q2JW8GGN
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50027595 (CHEMBL3356935) Show SMILES SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C27H35N3O4S/c31-25-15-8-14-24(29-25)27(33)30-23(13-5-2-6-16-35)26(32)28-18-21-11-7-12-22(17-21)34-19-20-9-3-1-4-10-20/h1,3-4,7,9-12,17,23-24,35H,2,5-6,8,13-16,18-19H2,(H,28,32)(H,29,31)(H,30,33)/t23-,24-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	658	n/a	n/a	n/a	n/a	n/a	n/a
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA Curated by ChEMBL					Assay Description Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay				J Med Chem 57: 8358-77 (2014) Article DOI: 10.1021/jm5008209 BindingDB Entry DOI: 10.7270/Q2JW8GGN
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50027595 (CHEMBL3356935) Show SMILES SCCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCc1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C27H35N3O4S/c31-25-15-8-14-24(29-25)27(33)30-23(13-5-2-6-16-35)26(32)28-18-21-11-7-12-22(17-21)34-19-20-9-3-1-4-10-20/h1,3-4,7,9-12,17,23-24,35H,2,5-6,8,13-16,18-19H2,(H,28,32)(H,29,31)(H,30,33)/t23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	504	n/a	n/a	n/a	n/a	n/a	n/a
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assay				J Med Chem 57: 8358-77 (2014) Article DOI: 10.1021/jm5008209 BindingDB Entry DOI: 10.7270/Q2JW8GGN
					More data for this Ligand-Target Pair