BDBM50027797 4-(8-Amino-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-yl)-benzene-1,2-diol::CHEMBL119555
SMILES: CN1CC(c2ccc(O)c(O)c2)c2cccc(N)c2C1
InChI Key: InChIKey=ODIYTWXTFQEXKZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50027797 (4-(8-Amino-2-methyl-1,2,3,4-tetrahydro-isoquinolin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Concentration that produces 50 % displacement of specific [3H]spiroperidol binding to rat caudate membrane preparations. | J Med Chem 27: 28-35 (1984) BindingDB Entry DOI: 10.7270/Q21J9BBG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cyclic AMP phosphoprotein (Rattus norvegicus) | BDBM50027797 (4-(8-Amino-2-methyl-1,2,3,4-tetrahydro-isoquinolin...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.88E+3 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Effective concentration that gives maximal stimulation of cyclic AMP production over the concentration range tested. | J Med Chem 27: 28-35 (1984) BindingDB Entry DOI: 10.7270/Q21J9BBG | |||||||||||
More data for this Ligand-Target Pair |